Comparison Between Reactive and Proactive Protocols of Wireless Sensor Networks: Railway Application

Railway is a critical application; hence, all systems that compose the railway infrastructure must meet two conditions: availability and safety. The availability ensures continuous operation of the system; on the other hand, safety is achieved when the device works properly regardless of the environmental or operating conditions. In addition, Wireless Sensor Networks (WSN) are used to perform tasks previously performed manually. However, it is necessary to analyse what protocol is appropriate for the railway industry, since availability and safety are the required attributes. In this work, a recently proposed routing protocol, the Multi-Parent Hierarchical (MPH), has been compared with a well-known protocol, the Ad-hoc On-Demand Distance Vector (AODV), in order to find the most suitable one for the railway applications. For this purpose, a simulator has been developed, which faithfully reifies the workings of a given protocol, considering a fixed, reconfigurable ad-hoc network given by the number and location of participants, and general network conditions.</p

FPGA based technical solutions for high throughput data processing and encryption for 5G communication: A review

The field programmable gate array (FPGA) devices are ideal solutions for high-speed processing applications, given their flexibility, parallel processing capability, and power efficiency. In this review paper, at first, an overview of the key applications of FPGA-based platforms in 5G networks/systems is presented, exploiting the improved performances offered by such devices. FPGA-based implementations of cloud radio access network (C-RAN) accelerators, network function virtualization (NFV)-based network slicers, cognitive radio systems, and multiple input multiple output (MIMO) channel characterizers are the main considered applications that can benefit from the high processing rate, power efficiency and flexibility of FPGAs. Furthermore, the implementations of encryption/decryption algorithms by employing the Xilinx Zynq Ultrascale+MPSoC ZCU102 FPGA platform are discussed, and then we introduce our high-speed and lightweight implementation of the well-known AES-128 algorithm, developed on the same FPGA platform, and comparing it with similar solutions already published in the literature. The comparison results indicate that our AES-128 implementation enables efficient hardware usage for a given data-rate (up to 28.16 Gbit/s), resulting in higher efficiency (8.64 Mbps/slice) than other considered solutions. Finally, the applications of the ZCU102 platform for high-speed processing are explored, such as image and signal processing, visual recognition, and hardware resource management

Comparison of Collaborative and Cooperative Schemes in Sensor Networks for Non-Invasive Monitoring of People at Home

This paper looks at wireless sensor networks (WSNs) in healthcare, where they can monitor patients remotely. WSNs are considered one of the most promising technologies due to their flexibility and autonomy in communication. However, routing protocols in WSNs must be energy-efficient, with a minimal quality of service, so as not to compromise patient care. The main objective of this work is to compare two work schemes in the routing protocol algorithm in WSNs (cooperative and collaborative) in a home environment for monitoring the conditions of the elderly. The study aims to optimize the performance of the algorithm and the ease of use for people while analyzing the impact of the sensor network on the analysis of vital signs daily using medical equipment. We found relationships between vital sign metrics that have a more significant impact in the presence of a monitoring system. Finally, we conduct a performance analysis of both schemes proposed for the home tracking application and study their usability from the user’s point of view

An Energy Model Using Sleeping Algorithms for Wireless Sensor Networks under Proactive and Reactive Protocols: A Performance Evaluation

The continuous evolution of the Internet of Things (IoT) makes it possible to connect everyday objects to networks in order to monitor physical and environmental conditions, which is made possible due to wireless sensor networks (WSN) that enable the transfer of data. However, it has also brought about many challenges that need to be addressed, such as excess energy consumption. Accordingly, this paper presents and analyzes wireless network energy models using five different communication protocols: Ad Hoc On-Demand Distance Vector (AODV), Multi-Parent Hierarchical (MPH), Dynamic Source Routing (DSR), Low Energy Adaptive Clustering Hierarchy (LEACH) and Zigbee Tree Routing (ZTR). First, a series of metrics are defined to establish a comparison and determine which protocol exhibits the best energy consumption performance. Then, simulations are performed and the results are compared with real scenarios. The energy analysis is conducted with three proposed sleeping algorithms: Modified Sleeping Crown (MSC), Timer Sleeping Algorithm (TSA), and Local Energy Information (LEI). Thereafter, the proposed algorithms are compared by virtue of two widely used wireless technologies, namely Zigbee and WiFi. Indeed, the results suggest that Zigbee has a better energy performance than WiFi, but less redundancy in the topology links, and this study favors the analysis with the simulation of protocols with different nature. The tested scenario is implemented into a university campus to show a real network running

Energy harvesting technologies and devices from vehicular transit and natural sources on roads for a sustainable transport: state-of-the-art analysis and commercial solutions

The roads we travel daily are exposed to several energy sources (mechanical load, solar radiation, heat, air movement, etc.), which can be exploited to make common systems and apparatus for roadways (i.e., lighting, video surveillance, and traffic monitoring systems) energetically autonomous. For decades, research groups have developed many technologies able to scavenge energy from the said sources related to roadways: electromagnetism, piezoelectric and triboelectric harvesters for the cars’ stress and vibrations, photovoltaic modules for sunlight, thermoelectric solutions and pyroelectric materials for heat and wind turbines optimized for low-speed winds, such as the ones produced by moving vehicles. Thus, this paper explores the existing technologies for scavenging energy from sources available on roadways, both natural and related to vehicular transit. At first, to contextualize them within the application scenario, the available energy sources and transduction mechanisms were identified and described, arguing the main requirements that must be considered for developing harvesters applicable on roadways. Afterward, an overview of energy harvesting solutions presented in the scientific literature to recover energy from roadways is introduced, classifying them according to the transduction method (i.e., piezoelectric, triboelectric, electromagnetic, photovoltaic, etc.) and proposed system architecture. Later, a survey of commercial systems available on the market for scavenging energy from roadways is introduced, focusing on their architecture, performance, and installation methods. Lastly, comparative analyses are offered for each device category (i.e., scientific works and commercial products), providing insights to identify the most promising solutions and technologies for developing future self-sustainable smart roads

Statistical study of user perception of smart homes during vital signal monitoring with an energy saving algorithm

Sensor networks are deployed in people’s homes to make life easier and more comfortable and secure. They might represent an interesting approach for elderly care as well. This work highlights the benefits of a sensor network implemented in the homes of a group of users between 55 and 75 years old, which encompasses a simple home energy optimization algorithm based on user behavior. We analyze variables related to vital signs to establish users’ comfort and tranquility thresholds. We statistically study the perception of security that users exhibit, differentiating between men and women, examining how it affects the person’s development at home, as well as the reactivity of the sensor algorithm, to optimize its performance. The proposed algorithm is analyzed under certain performance metrics, showing an improvement of 15% over a sensor network under the same conditions. We look at and quantify the usefulness of accurate alerts on each sensor and how it reflects in the users’ perceptions (for men and women separately). This study analyzes a simple, low-cost, and easy-to-implement home-based sensor network optimized with an adaptive energy optimization algorithm to improve the lives of older adults, which is capable of sending alerts of possible accidents or intruders with the highest efficiency

Wearable Urban Mobility Assistive Device for Visually Impaired Pedestrians Using a Smartphone and a Tactile-Foot Interface

This paper reports on the progress of a wearable assistive technology (AT) device designed to enhance the independent, safe, and efficient mobility of blind and visually impaired pedestrians in outdoor environments. Such device exploits the smartphone’s positioning and computing capabilities to locate and guide users along urban settings. The necessary navigation instructions to reach a destination are encoded as vibrating patterns which are conveyed to the user via a foot-placed tactile interface. To determine the performance of the proposed AT device, two user experiments were conducted. The first one requested a group of 20 voluntary normally sighted subjects to recognize the feedback provided by the tactile-foot interface. The results showed recognition rates over 93%. The second experiment involved two blind voluntary subjects which were assisted to find target destinations along public urban pathways. Results show that the subjects successfully accomplished the task and suggest that blind and visually impaired pedes-trians might find the AT device and its concept approach useful, friendly, fast to master, and easy to use

Non-random distribution of deleterious mutations in the DNA and protein-binding domains of IRF6 are associated with Van Der Woude syndrome

Background: The development of the face occurs during the early days of intrauterine life by the formation of facial processes from the first Pharyngeal arch. Derangement in these well-organized fusion events results in Orofacial clefts (OFC). Van der Woude syndrome (VWS) is one of the most common causes of syndromic cleft lip and/or palate accounting for 2% of all cases. Mutations in the IRF6 gene account for 70% of cases with the majority of these mutations located in the DNA-binding (exon 3, 4) or protein-binding domains (exon 7-9). The current study was designed to update the list of IRF6 variants reported for VWS by compiling all the published mutations from 2013 to date as well as including the previously unreported VWS cases from Africa and Puerto Rico.Methods: We used PubMed with the search terms; "Van der Woude syndrome," "Popliteal pterygium syndrome," "IRF6," and "Orofacial cleft" to identify eligible studies. We compiled the CADD score for all the mutations to determine the percentage of deleterious variants.Results: Twenty-one new mutations were identified from nine papers. The majority of these mutations were in exon 4. Mutations in exon 3 and 4 had CADD scores between 20 and 30 and mutations in exon 7-9 had CADD scores between 30 and 40. The presence of higher CADD scores in the protein-binding domain (exon 7-9) further confirms the crucial role played by this domain in the function of IRF6. In the new cases, we identified five IRF6 mutations, three novel missense mutations (p.Phe36Tyr, p.Lys109Thr, and p.Gln438Leu), and two previously reported nonsense mutations (p.Ser424*and p.Arg250*).Conclusion: Mutations in the protein and DNA-binding domains of IRF6 ranked among the top 0.1% and 1% most deleterious genetic mutations, respectively. Overall, these findings expand the range of VWS mutations and are important for diagnostic and counseling purposes.</p

Treatment with tocilizumab or corticosteroids for COVID-19 patients with hyperinflammatory state: a multicentre cohort study (SAM-COVID-19)

Objectives: The objective of this study was to estimate the association between tocilizumab or corticosteroids and the risk of intubation or death in patients with coronavirus disease 19 (COVID-19) with a hyperinflammatory state according to clinical and laboratory parameters. Methods: A cohort study was performed in 60 Spanish hospitals including 778 patients with COVID-19 and clinical and laboratory data indicative of a hyperinflammatory state. Treatment was mainly with tocilizumab, an intermediate-high dose of corticosteroids (IHDC), a pulse dose of corticosteroids (PDC), combination therapy, or no treatment. Primary outcome was intubation or death; follow-up was 21 days. Propensity score-adjusted estimations using Cox regression (logistic regression if needed) were calculated. Propensity scores were used as confounders, matching variables and for the inverse probability of treatment weights (IPTWs). Results: In all, 88, 117, 78 and 151 patients treated with tocilizumab, IHDC, PDC, and combination therapy, respectively, were compared with 344 untreated patients. The primary endpoint occurred in 10 (11.4%), 27 (23.1%), 12 (15.4%), 40 (25.6%) and 69 (21.1%), respectively. The IPTW-based hazard ratios (odds ratio for combination therapy) for the primary endpoint were 0.32 (95%CI 0.22-0.47; p < 0.001) for tocilizumab, 0.82 (0.71-1.30; p 0.82) for IHDC, 0.61 (0.43-0.86; p 0.006) for PDC, and 1.17 (0.86-1.58; p 0.30) for combination therapy. Other applications of the propensity score provided similar results, but were not significant for PDC. Tocilizumab was also associated with lower hazard of death alone in IPTW analysis (0.07; 0.02-0.17; p < 0.001). Conclusions: Tocilizumab might be useful in COVID-19 patients with a hyperinflammatory state and should be prioritized for randomized trials in this situatio

Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study

Background: The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on postoperative recovery needs to be understood to inform clinical decision making during and after the COVID-19 pandemic. This study reports 30-day mortality and pulmonary complication rates in patients with perioperative SARS-CoV-2 infection. Methods: This international, multicentre, cohort study at 235 hospitals in 24 countries included all patients undergoing surgery who had SARS-CoV-2 infection confirmed within 7 days before or 30 days after surgery. The primary outcome measure was 30-day postoperative mortality and was assessed in all enrolled patients. The main secondary outcome measure was pulmonary complications, defined as pneumonia, acute respiratory distress syndrome, or unexpected postoperative ventilation. Findings: This analysis includes 1128 patients who had surgery between Jan 1 and March 31, 2020, of whom 835 (74·0%) had emergency surgery and 280 (24·8%) had elective surgery. SARS-CoV-2 infection was confirmed preoperatively in 294 (26·1%) patients. 30-day mortality was 23·8% (268 of 1128). Pulmonary complications occurred in 577 (51·2%) of 1128 patients; 30-day mortality in these patients was 38·0% (219 of 577), accounting for 81·7% (219 of 268) of all deaths. In adjusted analyses, 30-day mortality was associated with male sex (odds ratio 1·75 [95% CI 1·28–2·40], p\textless0·0001), age 70 years or older versus younger than 70 years (2·30 [1·65–3·22], p\textless0·0001), American Society of Anesthesiologists grades 3–5 versus grades 1–2 (2·35 [1·57–3·53], p\textless0·0001), malignant versus benign or obstetric diagnosis (1·55 [1·01–2·39], p=0·046), emergency versus elective surgery (1·67 [1·06–2·63], p=0·026), and major versus minor surgery (1·52 [1·01–2·31], p=0·047). Interpretation: Postoperative pulmonary complications occur in half of patients with perioperative SARS-CoV-2 infection and are associated with high mortality. Thresholds for surgery during the COVID-19 pandemic should be higher than during normal practice, particularly in men aged 70 years and older. Consideration should be given for postponing non-urgent procedures and promoting non-operative treatment to delay or avoid the need for surgery. Funding: National Institute for Health Research (NIHR), Association of Coloproctology of Great Britain and Ireland, Bowel and Cancer Research, Bowel Disease Research Foundation, Association of Upper Gastrointestinal Surgeons, British Association of Surgical Oncology, British Gynaecological Cancer Society, European Society of Coloproctology, NIHR Academy, Sarcoma UK, Vascular Society for Great Britain and Ireland, and Yorkshire Cancer Research